Sunday, January 15, 2012

September 2001 issue, by the abstracts

This issue seemed to be about calorie restriction.  They all sound quite interesting.  Only abstracts available.

"Mechanisms of Prolonged Longevity: Mutants, Knock-Outs, and Caloric Restriction". Compares growth hormone receptor knock-out mice with calorie-restricted mice.

"Caloric Restriction in Nonmammalian Models". A review of what is known about calorie restriction in non-mammals, and molecular commonalities among them.

"Endocrine Effects of Dietary Restriction and Aging: The National Institute on Aging Study". More data from the long-term rhesus study. This is a summary of hormonal changes, maybe focusing on melatonin and DHEA.

"Progress in the Development of Caloric Restriction Mimetic Dietary Supplements". Review of initial studies on caloric restriction mimetics. They mention 2-deoxy-D-glucose, phenformin and iodoacetate as examples.

A review of a book on telomeres and telomerase from a symposium in 1997.

The literature review section looked at a paper that inserted mutant versions of the RNA template component of telomerase into immortal lines, and watched them slow down growth.

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