Interestingness: 4
By Simon Melov, Joanne Ravenscroft, Sarwatt Malik, Matt S Gill, David W Walker, Peter E Clayton, Douglas C Wallace, Bernard Malfroy, Susan R Doctrow and Gordon J Lithgow, in Science 1 September 2000, Volume 289, Issue 5484 (pp 1567-1569 DOI: 10.1126/science.289.5484.1567 )
This is one of the papers that was being reviewed in the gerontology review of the Journal of Anti-Aging Medicine. This supposed superoxide dismutase and catalase mimetics (EUK-8 and EUK-134), extend the average lifespan of C Elegans by 44%. Maximum lifespan also seems to go up by about that much. Strangely to me, the effect is not dose dependent, which they explain it to be due it most likely being ingested, and because they stop eating when they are old, the effect is self-limitting or something like that, but I don't see how that explanation explains much. Nice strong effect anyway.
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