Age-Associated Plasma Lipids, Lipid Peroxidation, and Antioxidant Systems in Relation to Vitamin C Supplementation in Humans

Interestingness: 2

By Muthuvel Jayachandran, Palaniyappan Arivazhagan and Chinnakkannu Panneerselvam, in the Journal of Anti-Aging Medicine, Volume 3, Issue 4, 2000 (pp 437-445, doi:10.1089/rej.1.2000.3.437.)

They looked at vitamin C, cholesterol, lipid peroxides, and a whole bunch of antioxidants (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glutathione S-transferase) in young (20-30 year olds) and old (> 60 year olds) and see that antioxidants in old are lower, cholesterol and lipids are higher in old people. They give both groups 200 mg/day of vitamin C for 90 days.  All numbers in old people get a lot better.

I'd have been more interested if I didn't already "know" that vitamin C does nothing good for mortality.