Issue 3, 2004

By the abstracts:

"Regulation of Murine Telomere Length via Rtel". What the title says. Rtel being a DNA helicase-like protein gene. Hadn't heard about it.

"Mitochondrial Mutations in Mammalian Aging: An Over-Hasty About-Turn?". This seems, from the abstract, to be de Grey chastising the community both for ignoring mtDNA mutations and then for changing their mind too easily due to a study of a mouse with accelerated mtDNA mutations in which it had aging-like issues.  Sounds interesting.

"The Interdependence of Skin Aging, Skin Cancer, and DNA Repair Capacity: A Novel Perspective with Therapeutic Implications". Review of effects of UV light on skin DNA, and repair against those effects.

"Rejuvenation of Visual Functions in Older Adult Drivers and Drivers with Cataract During a Short-Term Administration of N-Acetylcarnosine Lubricant Eye Drops". RCT of N-acetylcarnosine on 130 people, half of them with cataracts. They seem to think it works at reducing glare sensitivity.

"Paradoxes of Non-Trivial Gene Networks: How Cancer-Causing Mutations Can Appear to Be Cancer-Protective". Model paper supposedly showing how certain alleles that seem onco-protective could actually be onco-causal. Maybe interesting.

Commentary on "A Policy Analysis of Funding for Ambitious Interventional Gerontology: The Possibility of Rejuvenation Research at the National Institute on Aging" about how to get rejuvenation research structured/funded under the National Institute of Aging.

"Science and Politics: World Events Intensify Stem Cell Debate". Some supposed-to-be report about the First International Stem Cell Action Conference, but which seems to be commentary on the US political situation on stem cell research.

A report of the "Regenerate 2004: Tissue Engineering the Human Body, June 10–12, 2004, Seattle" meeting. These are always fun to read.  A bit of a downer in that the topics discussed sound very similar to what I keep reading about currently.