Issue 2, 2004

By the abstracts:


"Inter-Species Therapeutic Cloning: The Looming Problem of Mitochondrial DNA and Two Possible Solutions". Title seems like a good summary.

"Catecholamines and Protein Deposition in Parkinson's and Alzheimer's Disease: Old Medicine, New Targets". Didn't get to the meat. Catecholamines, wiki says, are compounds that have a catechol, which is a benzene with two hydroxil groups attached. eg epinephrine, dopamine.

"A Reproducible Laser-Wounded Skin Equivalent Model to Study the Effects of Aging In Vitro". Trying to create a model of partial wounds on skin (by partial meaning not through the whole thing). They like the look of the wounds produced by a low powered excimer laser (excimer lasers emit UV, wiki tells me).

"Selective Pressure for a Decreased Rate of Asymmetrical Divisions Within Stem Cell Niches May Contribute to Age-Related Alterations in Stem Cell Function". The abstract claims that there is a selection pressure for stem cells to reproduce symmetricaly, and thus produce two stem cells, and probably cancer, but this paper is about a second independent pressure against asymmetrical division of stem cells. Sounds interesting.

"Telomeres and Telomerase: A Modern Fountain of Youth?". Discusses whether telomerase will be used for anti-aging therapies.  They think not.  Want to read the rest, or, more likely, an updated version of it.

"Aging Theories of Primary Osteoarthritis: From Epidemiology to Molecular Biology". Seems to be a review paper on osteoarthritis. Very well cited.

A review of the book "Cells, Aging, and Human Disease" by Michael Fossel