Monday, December 26, 2011

Glucagon-Like Peptide 1 (GLP-1) in Diabetes and Aging

By David D'Alessio in the Journal of Anti-Aging Medicine, Volume 3, Issue 3, 2000.

Interestingness: 2

I'd never heard of GLP-1, but it seems to accentuate the glucose-lowering effect of insulin, by including but maybe not limiting to, increasing insulin secretion. Maybe also acts as a satiety marker. GLP-1 is synthesised in the intestines. Glucose eaten has much higher effect on increasing insulin than glucose injected.  Lots of problems in studies caused by mixing detection of active and inactive form of the peptide.

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